Aarti Aunty

The best way to Organize Full Genome Sequencing

Genomics is a subject of technology that changes at an alarmingly rapid rate. It’s difficult to locate examples of other fields which have undergone change at similar rates, but comparisons could are the evolution of computer technology over the past several decades or the rapid growth of Internet startups in the 90s. Unlike these examples, the growth of genome sequencing technology is restricted to a certain technological sector, or at least, it has been until now.

Sequencing technology has become passing a vital point, where the expense of whole genome sequencing is clearly lower than the expense of running a conventional panel of genetic tests. Although it is difficult to calculate an exact figure for this, it probably lies in the product range of $1K-$10K. Illumina’s HiSeq platform or IonTorrent’s Proton both promise genomic sequencing in this range, as well as Complete Genomics. Even as we pass this aspect, genome sequencing moves from the realm of research technology to viable clinical diagnostic test.

The effects of this change can be observed in the growing widespread curiosity about sequencing technology. While technologies of this type have revolutionized many areas of research over the past decade, their use within clinical settings has profound implications for this industry. Research applications can only just provide a small source of profits. Getting into clinical applications provides usage of a bigger quantity of capital, both due to the larger market and higher profit margins.

The clinical introduction of genome sequencing technology will change many aspects of healthcare next few years. Genome sequencing could eventually take the spot of a typical section of a patient’s healthcare record, in quite similar way as blood type and allergies to medication are utilized today. علم الوراثة However, we have plenty of ground to cover before we get to the point. For entrepreneurs in this field, this equates to a selection of exciting opportunities.

While interpretation of genomic has been an important area of research, the growing use of this data in clinical fields will create a good demand for the unambiguous interpretation of results. Physicians want an unambiguous questions such as disease predisposition, and they’d like a respected party to assume the responsibility for causeing the judgement. Recently, an increasing amount of companies have entered the location of genomic data interpretation, many of them small startups such as Genformatic, a Bioinformatics company situated in Austin. Larger companies also have begun to concentrate on providing these services. As this industry evolves, it is likely that more companies may enter this realm, and it will undoubtedly be interesting to observe how things develop in this area.

While a person with experience in Molecular Biology possesses the necessary skills to organize and run libraries, plenty of things can go wrong in this process. Even yet in pure research applications, sample preparation is an increasingly common service supplied by a number of centers, as well as boutique services, such as Genome Organizer’s ChIP-Seq service. It’s not too researchers can’t perform these tasks, nevertheless when they are available for a fee, they see little benefit to running these services for themselves. As genomic sequencing moves into the clinical realm, demand for such services can be expected to increase. There are not many hospitals with the existing capability to perform basic sample preparation, and this represents a fresh area of opportunity in this field.

One of many greatest areas of uncertainty of this type today is how samples can get from physicians’ offices to sequencing centers, and who’ll inform patients of the results. Though medical school curricula may 1 day are the interpretation of genomic data, we’re not even close to that point today. Currently, even the administration and interpretation of Genetic tests is generally left to individuals in the field of Genetic Counseling, in collaboration with statisticians and specialists. Although it is likely that a selection of other professionals will take control the responsibility of this field as time goes on, it is likely that in the longer term, the growth will need place in this field.